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This video demonstrates the use of thrombin in the percutaneous treatment of a narrow necked splenic artery pseudoaneurysm:
The thrombin component of Tisseel was used.
The first reported cases of thrombin injection for aneurysms and pseudoaneurysms were in 1986:
Cope C, Zeit R. Coagulation of Aneurysms by Direct Percutaneous Thrombin Injection. AJR 1986;147:383-7.
Since then we reported our experience using percutaneous thrombin injection with and without balloon occlusion of the parent vessel:
Loose HW,.Haslam PJ. The management of peripheral arterial aneurysms using percutaneous injection of fibrin adhesive. Br.J.Radiol. 1998;71:1255-9. (13 cases balloon)
Owen RJ, Haslam PJ, Elliott ST, Rose JD, Loose HW. Percutaneous ablation of peripheral pseudoaneurysms using thrombin: a simple and effective solution. Cardiovasc.Intervent.Radiol. 2000;23:441-6. (25 cases, 19 with balloon)
The technique has become widely established in the treatment of pseudoaneurysms.
Dr Phil Haslam Consultant Interventional Radiologist
Dr Rob Williams Consultant Interventional Radiologist
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Thank you for your wonderful procedure.
After thrombin injection procedure, do you recommend follow up contrast enhanced CT scan ?? (to check post procedure status of pseudoaneurysm or complication such as distal embolization of thrombin to distal splenic artery or pancreatic arterial branches).