Smith & Nephew | Supartz | Which Medical Device
From Which Medical Device
Supatrz(R) is a sterile mixture containing purified sodium hyaluronate, from chicken combs. In animal models, Supartz(R) increased the integrity of the cartilage, reduced the cell death rate and improved the overall joint morphology. It also reduced synovitis, stimulated the production of endogenous HA and penetrated to the damaged cartilage promoting repair. In a large-animal model Supartz(R) significantly increased the production of endogenous hyaluronic acid in synovial tissue. Finally it has also been proven to reduce levels of pro-inflammatory cytokines and the production of cartilage-degrading enzymes in cultured cells.
Reported side effects include pain, oedema, erythema, warmth or bruising at the site, and headache, temperature and tingling skin. Serious allergic reaction to Supartz(R) has been described but is rare.
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