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Hyaluronic acid for injection
From Which Medical Device
Synvisc(R) is an elastoviscous fluid of high molecular weight, containing hylan A and hylan B polymers produced from chicken combs. Hylan A and B are derivatives of hyaluronic acid. It is indicated for the relief from pain in osteoarthritis (OA) in patients who have not responded satisfactorily to conservative non-pharmacologic therapy.
Synvisc comes in two different formulations, SYNVISC(R) and SYNVISC-One(R). SYNVISC-One(R) is a single dose treatment, compared with the three injections required with SYNVISC(R).
As with other preparations, it should not be administered to patients with infected joints, with active skin disease or with any skin infection around the area where the injection will be given. Reported side effects include (<2% each): pain, swelling, heat, redness, and/or oedema around the joint.
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